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Analgesic and antipyretic activity of leaves of Annona muricata

R.A.Shastry, P.V.Kulkarni, V.H.Kulkarni B.S.Patil, P.V.Habbu

Annona muricata Linn. (Fam:Annonaceae) is a widely claimed medicinal plant with wide ranging biological activities. In the present study, ethanolic and aqueous extracts of leaves of Annona muricata was screened for analgesic and antipyretic activity in albino rats using various experimental models viz acetic acid induced writhing method, hot plate method and yeast induced pyrexia. The ethanolic extract (500 mg/kg, p.o) exhibited significant analgesic and antipyretic activity as compared to aqueous extract.