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Anti-Inflammatory Activity of Ethanol Extract of Leaf and Bark of Feronia Elephantum Correa

A. Muthulakshmi, R. Jothibai Margret and V. R. Mohan

Ethanol extract of Feronia elephantum leaf and bark were investigated for its anti-inflammatory activity in animal models. The anti-inflammatory activity was estimated volumetrically by measuring the mean increase in hind paw volume of rat with the help of plethysmometer. Indomethacin in the dose of 10 mg/Kg is used as standard drug. The plant extracts were given in the doses of 200 and 400 mg/Kg body weight. Control group received 0.5% NaCl (saline) solution. All the doses were administered orally. Results showed that, ethanol extract of leaf had potent and significant anti-inflammatory activity.