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Antimicrobial Study of 1,1-Bis- {2-hydroxy-3-(1-phenyl-5-aryl-pyrazolin 3- yl)-5 methyl phenyl} methane

Rajesh P. Ganorkar

Titled bis-pyrazolines have been synthesized by condensation of phenylhydrazine hydrochloride with bis-chalcones in pyridine medium. All compounds have been evaluated for their in vitro growth of inhibitory activity against Staphylococcus aureus, Escherichia coli, Proteus mirabilis and Salmonella Typhi using paper disc-method. The culture medium was nutriert agar medium. Most of the titled bispyrazolines were more or less effective against these microorganisms.