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Application of nanoparticles in quartz crystalmicrobalance biosensors

Somayeh Heydari, Gholam Hossein Haghayegh

Nanoparticles are playing an increasingly important role in the development of biosensors. The sensitivity and performance of biosensors is being improved by using Nanoparticles for their construction. The use of these Nanoparticles has allowed the introduction of many new signal transduction technologies in biosensors. In this report, a comprehensive review of Application of nanoparticles in Quartz Crystal Microbalance biosensors is presented. The main advantages of QCM in sensing fields include high sensitivity, high stability, fast response and low cost. In addition, it provides label-free detection capability for bio-sensing applications.Firstly, basic QCMÂ’s design and characterization are described. Next, QCM biosensors based on modification of quartz substrate structure and their applications are digested. Nanoparticles and their utilizationin analysis are then illustrated. These include Nanoparticles in bio applications that cover Nanoparticles in Quartz Crystal Microbalance biosensors.