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Catalytic-Free Highly Efficient and Eco-Friendly Protocol for the Synthesis of Semicarbazones at Ambient Temperature

Janardhan Banothu and Rajitha Bavantula

Highly efficient procedure for the synthesis of semicarbazones has been developed by the reaction of arylaldehydes/acetophenones/3-acetyl coumarins with semicarbazide hydrochloride under catalytic free conditions in aqueous methanol at ambient temperature in excellent yields. All the compounds were characterized by their analytical and spectral data