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Chemical composition in different parts of the ethanol extract from zanthoxylum avicennae and antimicrobial activity

Yu-xian Li, Nan-nan Zheng, Ke Yuan

Zanthoxylum avicennae is a species of Rutaceae with some bioactivity. The contents of Total flavonols(TF) and Total phenolic acids(TP) and antifungal activities of the six parts of the ethanol extract of Zanthoxylum avicennae were evaluated. Total flavonols (TF) content was estimated by NaNO2-Al(NO)3 colorimetric assay and Total phenolic acids (TP) content was determined using the Folin–Ciocalteu method with a slight modification,while Minimum inhibitory concentration (MIC) was determined using the tube double-dilution technique. The results of the experiments can find the 40% n-BuOH fraction has the strongest antifungal activity, meanwhile having the highest contents of TF and TP,thus providing scientific data for Zanthoxylum avicennae further development and exploitation.