抽象的な

Comparative studies on the interaction of tartrazine with bovine serum albumin by fluorescence quenching spectroscopy and synchronous fluorescence spectroscopy

Lihui Zhang, Baosheng Liu, Zhiyun Li, Ying Guo, Yunkai Lv


Under simulated physiological conditions, the reactionmechanismbetween tartrazine (TTZ) and bovine serumalbumin (BSA) at different temperatures (293 K, 303 K, 310 K)was investigated by fluorescence quenchingmethod and synchronous fluorescence method, respectively. The results indicated that the fluorescence intensity and synchronous fluorescence intensity of BSA decreased regularly with the addition of TTZ, in addition, the quenching mechanism, binding constants (Ka), the number of binding site (n), type of interaction force and energy transfer parameters of TTZ with BSA obtained from two methods by the same equation were consistent, which indicated synchronous fluorescence spectrometrywas a newmethod of studying the binding mechanism between drug and protein, and it was a useful supplement to the classical method.


免責事項: この要約は人工知能ツールを使用して翻訳されており、まだレビューまたは確認されていません

インデックス付き

  • キャス
  • Google スカラー
  • Jゲートを開く
  • 中国国家知識基盤 (CNKI)
  • サイテファクター
  • コスモスIF
  • 電子ジャーナルライブラリ
  • 研究ジャーナル索引作成ディレクトリ (DRJI)
  • 秘密検索エンジン研究所
  • ICMJE

もっと見る

ジャーナルISSN

ジャーナル h-インデックス

Flyer

オープンアクセスジャーナル