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Design and Comparison of Periodontal Strips of Gatifloxacin for Periodontal Diseases

K. Kanthraj, Mohammed Gulzar Ahmed, R. Narayana Charyulu, P. S. Minhas, B. V. Chandrashekharappa, H. A. Ramesh and D. V. Kishore Kumar

Treatment of periodontitis aims at eradicating or controlling specific pathogens. Antibiotics are prime candidates for patient with recently diagnosed active periodontitis. In antimicrobial susceptibility, profile may cause periodontitis. The purpose of this study was to design different polymeric strips containing same concentration of drug, ability to control and compare drug release characteristics by cross-linking and to study various pharmacokinetic parameters like physicochemical, stability and mass balance studies.