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In Vitro Antioxidant Study of Petroleum Ether, Chloroform and Ethyl Acetate Fractions of Coccinia Grandis L. Voigt Stem Extract

S. V. Deshpande, M. J. Patil, S. C. Daswadkar, R. S. Telekone and R. S. Kale

The present study aimed at investigating the antioxidant activities of the petroleum ether, chloroform and ethyl acetate fractions of the stem extract of Coccinia grandis L.Voigt (Cucurbitaceae). The antioxidant activities of the fractions have been evaluated by using four in vitro assays and were compared to standard antioxidant as butylated hydroxy anisole (BHA). All the fractions showed effective H-donor activity, reducing power and free radical scavenging activity. The antioxidant property depends upon concentration of the fractions, which may be attributed to the presence of phenolic and flavonoid compounds present in the fractions. The results obtained in the present study indicate that the stem of C. grandis may be a potential source of natural antioxidant.