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Iron (III) Phosphate as an Efficient and Reusable Catalyst for the Synthesis of 1,5-Benzodiazepines

Shahnavaz V, Farahnaz KB*

Iron (III) phosphate was used as an efficient catalyst for the preparation of 1,5-benzodiazepines in excellent yields. This method is applicable for the reaction of o-phenylenediamines with cyclic or acyclic ketones. The salient features of the present methodology are cheaper process and catalyst and in addition, the catalyst can be easily recovered after completion of the reaction and reusable without affecting its activity.