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Microwave Assisted Rapid Synthesis of 3, 4-Dihydropyrimidine-2-(1H)-Ones/Thiones Using LSA as a Catalyst under Solvent Free Conditions

Sadhana N. Chamle, Manjusha V. Yadav and Ashok D. Sagar

Lignin Sulphonic Acid (LSA) was found to be an efficient catalyst for the synthesis of 3, 4- dihydropyrimidin-2-(1H)-ones/thiones from the multicomponent condensation reaction of aromatic aldehyde, ethyl acetoacetate and urea / thiourea in solventfree condition on microwave at 180 W.