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Pharmacological Activities Of Two New 8-Hydroxy quinoline Derivatives

B.Himmi, My A.Faouzi, M.Akioud, S.Kitane, A.Eddaif, M.Soufiaoui, S.Ghoulidi, A Bahloul, Et A.Sebban, Y.Cherrah

In thiswork, the acute experimental toxicity of two new8-hydroxyquinoline derivatives products was evaluated following oral administration in mice(IopsOfa). The LD50obtainedwere 283.70mg/kg for(2a) and >3000mg/ kg for(2b). Their in vitro antibacterial and antifungal activities were evaluated against reference strains.