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Phytochemical Investigations and Hepatoprotective Effects of Aqueous Fruit Extract of Aegle Marmelos Corr.

A. V. S. Sastry, V. Girija Sastry, G. Naga Sandhya and K. Srinivas

Aegle marmelos Correa (Rutaceae), commonly known as Bael has been used in ethno-medicine to exploit it’s medicinal properties including astringent, antidiarrheal, antidysentric, dermulcent, antidiabetic and anti-inflammatory activities. Aegle marmelos Corr. is widely used in the treatment of hepatitis in folk medicine. Owing to its overwhelming ethnomedicinal significance, it is proposed to investigate it chemically and to verify the hepatoprotective activity of the crude aqueous extract of the fruit of Aegle marmelos. A novel compound was isolated from the aqueous fruit extract. The aqueous crude extract showed significant hepatoprotective activity in Wistar albino rats treated with paracetamol.