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Production optimization, characterization and antimicrobial activity of pyocyanin from Pseudomonas aeruginosa SPC B 65

Abraham Mathew, Abi N.Eldo, A.G.Molly

Siderophores can act as biostatic compounds by drastically reducing the amount of ferric ions available to microbes. Pyocyanin, produced by Pseudomonas aeruginosa was found to show anti bacterial and anti fungal activities.Of the various parameters optimized, a temperature of 35° C, pH of 7.5 and ferric chloride concentration of 10 µM was found to be optimumfor pyocyanin production.Maximumpyocyanin production was noticed in the absence of NaCl. High thermostability was also noted for the pigment.