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Simultaneous determination of ephedrine-hydrochloride and dopamine at poly 1, 8- diaminonaphthaline derivatives modified platinum electrode

A.A.Hathoot, E.A.Khudaish, M.S.Fahmy, M.Abdel Azzem

Simultaneous determination of ephedrine hydrochloride (Eph) and dopamine (DA) at poly 8-(3-acetylimino-6-methyl-2, 4-dioxpyran)-1- aminonaphthalene modified platinum electrode (PAMDAN/Pt) was developed at PAMADAN/Pt, the peaks of Eph and DAappear at 0.120 and 0.550 V in pH 3.2. PAMADAN/Pt does not only accelerate the oxidation of Eph and DA, but also enlarges dramatically the peak separation between Eph and DA. The PAMADAN/Pt was successfully applied to detect Eph in pharmaceutical samples and human blood serum.