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Synthesis and characterization of the new type of tetrazoles containing barbiturates

Mahdokht Rezazadeh, Amin Azimian

Tetrazoles undergo various reactions such as alkylation and acylation, complex formationwithmetals, thermolysis, photolysis, and decompositionwith formation of nitrenes, etc. At first we synthesis cyanogen bromide and reaction with phenolic derivatives and phenyl cyanate derivatives (Aryl cyanate), including derivative 5– phenoxy tetrazole are obtained. Then reaction of derivatives phenyl cyanate with sodium azide are resulted relevant tetrazole thenwith using ofVilsmeier reagent the corresponding composition para position can Formylation. This is formyled derived from 5– phenoxy tetrazole never has been synthesized. Tetrazoles derivatives were synthesized and characterized by using FT-IR, NMR.