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Synthesis and Microbial Study of Some Novel Cyanopyrans and Cyanopyridines Containing Imidazole Nucleus

Hitendra K. Maheta, Anil S. Patel and Yogesh T. Naliapara

The desired fused ring system cyanopyrans 4 were synthesized by the reaction of chalcones 3 with malononitrile in pyridine while chalcones 3 on reaction with malononitrile in presence of ammonium acetate in methanol yielded cyanopyridines 5. Their IR, 1 H NMR, mass spectral data and elemental analyses were in accord with assigned structures.