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Synthesis, Characterization and Antibacterial Study Of Novel Schiff Base Ligand With Some Metal Ion Co(Ii), Ni(Ii), Cu(Ii) And Zn(Ii)

Batool Qusai Ali, Mohammed Hamid Said and Rasha Hasan Jasim

A new Schiff base ligand has been synthesized through the condensation of amino penicillinic acid with o-nitrobenzyldehyde dissolved in absolute ethanol in alkaline medium. Metal complexes of the Schiff base have been synthesized from chloride salt of Co(II), Ni(II), Cu(II) and Zn(II) metal in the alcoholic medium. Different analytical and diagnostic techniques UV-Vis spectrum, IR spectroscopy, mass spectrum, (H,C) NMR spectrophotometry, magnetic susceptibility studies and molar conductivity have been used in the investigation of prepared compound properties and their proposed stereochemistry. The effectiveness of inhibitory compounds prepared was against tested four types of bacteria (Staphylococcus aureus, pseudomonas aeruginosa, Streptococcus facials and Proteus mirabilis), which were isolated from different classes of ulcerative infections.