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Synthesis, characterization and antimicrobial activity of metal complexes of hydrazone derivative of 8-aceto-7-hydroxy–coumarin

Gaurang Jani, Kartik Vyas, Kiran Nimavat, Denish Karia, Judas Franco

The metal complexes of Cu(II), Ni(II), Fe(II), Co(II) and Fe(III) with hydrazone derivative of coumarin have been synthesized and characterized using elemental analysis, magnetic susceptibility and IR spectra. Taking in to account, their importance in therapeutic field of research, these compounds were studied for their antimicrobial activity. The paper discs or agar diffusion technique was used. This study show net enhancement in activity on co-ordination of metals with ligand but moderate activity as compare to standard drugs.