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Synthesis, Characterization and Biological Investigations on Metal Complexes of 2- [5-Acetyl-2, 4-Dihydroxybenzyl]-1H-Isoindole-1, 3 (2H) - Dione

M. R. Solanki, G. D. Acharya and M. V. Hathi

The more significant biologically active Cu (II), Ni (II), Co (II) and Mn (II) complexes were synthesized by using N-hydroxymethyl phthalimide and 2,4-dihydroxyacetophenone as ligand. Synthesized complexes were characterized by elemental analysis, conductance, magnetic susceptibility, IR and reflectance spectral studies. Coordination of the ligand atom to the metal ion was deduced by IR and reflectance spectral data. Structures of the complexes were also confirmed by magnetic studies. All the complexes have been screened for antibacterial and antifungal activities.