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Synthesis, Characterization of Novel Quinazoline Derivatives and Antimicrobial Screening

Srinivasa Rao Dasari, Lakshmana Rao Vadali and Tondepu Subbaiah

A novel series of compounds were synthesised by C-C bond formation of substituted quinazolinones (1) with substituted boronic acids (2) to get 2,4-disubstituted quinazoline (3a-3j) target compounds under mild conditions with good yields. The structures of new compounds were confirmed by IR and 1H NMR and 13C NMR spectral data.