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The Interaction of Interfacial Hydrophobicity and Hydroxylation Activity in Fungal Cells at an Organic-Aqueous Interface

Gloria Simmons

A Liquid–liquid interface bioreactor (L–L IBR), that consists of a hydrophobic organic solvent (an higher phase), a layer of fungous cellballooned polyacrylonitrile microsphere (diameter, 20-40 μm; density, 0.03-0.20; a middle phase), and a liquid medium (a lower phase), is a unique and effective cultivation system for the microorganism transformation with fungi. The system has some attentiongrabbing and practically necessary characteristics, i.e., alleviation of toxicity of poisonous substrate and/or product solubilized within the organic part, excellent productivity of valuable hydrophobic chemicals, efficient supply of element from the organic part to fungous cells, management and management of pH and nutrients within the liquid medium, depression of catabolize repression caused by simply metabolizable carbon sources, and simple recovery of product while not hard solvent extraction.